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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASH1L
All Species:
21.82
Human Site:
Y1517
Identified Species:
48
UniProt:
Q9NR48
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR48
NP_060959.2
2969
332790
Y1517
V
L
E
S
L
K
R
Y
R
F
G
K
D
A
V
Chimpanzee
Pan troglodytes
XP_513861
2964
332149
Y1517
V
L
E
S
L
K
R
Y
R
F
G
K
D
A
V
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851926
2974
332800
Y1517
V
L
E
S
L
K
R
Y
R
F
G
K
E
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q99MY8
2958
331289
Y1514
V
L
E
S
L
K
R
Y
R
F
G
K
D
T
V
Rat
Rattus norvegicus
NP_001101159
2918
326454
Y1514
V
L
E
S
L
K
R
Y
R
F
G
K
D
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511389
1395
154154
I119
A
A
P
P
P
S
P
I
N
S
Q
S
Q
P
S
Chicken
Gallus gallus
XP_422858
2954
330578
Y1506
V
L
E
S
L
K
R
Y
R
F
G
K
E
A
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692254
2962
327377
A1487
R
F
G
R
D
G
S
A
D
S
R
T
N
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW15
2226
246247
G950
T
L
L
H
K
T
G
G
N
L
L
L
K
R
K
Honey Bee
Apis mellifera
XP_001122948
2180
246181
D904
S
D
K
I
E
K
R
D
L
S
P
E
H
V
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784903
3312
363645
Q1850
S
L
L
A
N
L
T
Q
R
T
S
T
V
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
94.1
N.A.
91.7
91.2
N.A.
21.5
79.9
N.A.
40.9
N.A.
26.1
26
N.A.
27.3
Protein Similarity:
100
99.6
N.A.
97
N.A.
95.3
94.4
N.A.
31.8
89.2
N.A.
53
N.A.
42.2
43.9
N.A.
43.3
P-Site Identity:
100
100
N.A.
86.6
N.A.
93.3
93.3
N.A.
0
93.3
N.A.
0
N.A.
6.6
13.3
N.A.
20
P-Site Similarity:
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
0
100
N.A.
6.6
N.A.
6.6
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
0
0
0
10
0
0
0
0
0
37
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
10
10
0
0
0
37
0
0
% D
% Glu:
0
0
55
0
10
0
0
0
0
0
0
10
19
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
55
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
10
10
10
0
0
55
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
10
64
0
0
0
0
0
55
10
10
10
% K
% Leu:
0
73
19
0
55
10
0
0
10
10
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
19
0
0
0
10
0
0
% N
% Pro:
0
0
10
10
10
0
10
0
0
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
10
0
10
0
10
% Q
% Arg:
10
0
0
10
0
0
64
0
64
0
10
0
0
10
10
% R
% Ser:
19
0
0
55
0
10
10
0
0
28
10
10
0
0
19
% S
% Thr:
10
0
0
0
0
10
10
0
0
10
0
19
0
28
0
% T
% Val:
55
0
0
0
0
0
0
0
0
0
0
0
10
10
55
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
55
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _